JPH0437806B2 - - Google Patents

Info

Publication number
JPH0437806B2
JPH0437806B2 JP58122945A JP12294583A JPH0437806B2 JP H0437806 B2 JPH0437806 B2 JP H0437806B2 JP 58122945 A JP58122945 A JP 58122945A JP 12294583 A JP12294583 A JP 12294583A JP H0437806 B2 JPH0437806 B2 JP H0437806B2
Authority
JP
Japan
Prior art keywords
hbsag
gel
freeze
aluminum
hepatitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58122945A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6013718A (ja
Inventor
Kyosuke Mizuno
Yoshimitsu Ishihara
Tetsuo Kawahara
Shinya Ootomo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KAGAKU OYOBI KETSUSEI RYOHO KENKYUSHO
Original Assignee
KAGAKU OYOBI KETSUSEI RYOHO KENKYUSHO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14848502&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0437806(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by KAGAKU OYOBI KETSUSEI RYOHO KENKYUSHO filed Critical KAGAKU OYOBI KETSUSEI RYOHO KENKYUSHO
Priority to JP58122945A priority Critical patent/JPS6013718A/ja
Priority to AU29993/84A priority patent/AU572162B2/en
Priority to KR1019840003814A priority patent/KR910005888B1/ko
Priority to EP84107773A priority patent/EP0130619B1/en
Priority to DE8484107773T priority patent/DE3477139D1/de
Priority to AT84107773T priority patent/ATE41309T1/de
Priority to CA000458226A priority patent/CA1237076A/en
Publication of JPS6013718A publication Critical patent/JPS6013718A/ja
Publication of JPH0437806B2 publication Critical patent/JPH0437806B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
JP58122945A 1983-07-05 1983-07-05 Ｂ型肝炎ワクチン Granted JPS6013718A (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP58122945A JPS6013718A (ja) 1983-07-05 1983-07-05 Ｂ型肝炎ワクチン
AU29993/84A AU572162B2 (en) 1983-07-05 1984-06-28 Hepatitis b vaccine
KR1019840003814A KR910005888B1 (ko) 1983-07-05 1984-07-02 동결건조 b형 간염 왁진의 제조방법
EP84107773A EP0130619B1 (en) 1983-07-05 1984-07-04 Hepatitis b vaccine and method for its preparation
DE8484107773T DE3477139D1 (en) 1983-07-05 1984-07-04 Hepatitis b vaccine and method for its preparation
AT84107773T ATE41309T1 (de) 1983-07-05 1984-07-04 Hepatitis-b-vakzin und verfahren zur herstellung.
CA000458226A CA1237076A (en) 1983-07-05 1984-07-05 Hepatitis b vaccine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58122945A JPS6013718A (ja) 1983-07-05 1983-07-05 Ｂ型肝炎ワクチン

Publications (2)

Publication Number Publication Date
JPS6013718A JPS6013718A (ja) 1985-01-24
JPH0437806B2 true JPH0437806B2 (en]) 1992-06-22

Family

ID=14848502

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58122945A Granted JPS6013718A (ja) 1983-07-05 1983-07-05 Ｂ型肝炎ワクチン

Country Status (7)

Country Link
EP (1) EP0130619B1 (en])
JP (1) JPS6013718A (en])
KR (1) KR910005888B1 (en])
AT (1) ATE41309T1 (en])
AU (1) AU572162B2 (en])
CA (1) CA1237076A (en])
DE (1) DE3477139D1 (en])

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60193925A (ja) * 1984-03-13 1985-10-02 Chemo Sero Therapeut Res Inst 凍結乾燥製剤化ワクチン
EP0294071A3 (en) * 1987-06-03 1990-08-01 Merck & Co. Inc. Hepatitis b vaccines made with pre-formed aluminum hydroxide gels, and processes thereof
EP0835663B1 (en) * 1992-05-23 2009-09-30 GlaxoSmithKline Biologicals S.A. Combined vaccines comprising Hepatitis B surface antigen and other antigens
WO1994007469A1 (en) * 1992-09-25 1994-04-14 Dynagen, Inc. An immunobooster for delayed release of immunogen
US6051238A (en) * 1996-12-20 2000-04-18 Merck & Co., Inc. Stabilizers for lyophilized mumps vaccines
US6290967B1 (en) * 1996-12-20 2001-09-18 Merck & Co., Inc. Stabilizers for lyophilized vaccines
JP2003535119A (ja) * 2000-06-08 2003-11-25 パウダージェクト ワクチンズ，インコーポレーテッド 粉末組成物
UA79735C2 (uk) 2000-08-10 2007-07-25 Глаксосмітклайн Байолоджікалз С.А. Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах
EP1399131A2 (en) 2001-06-08 2004-03-24 Powderject Vaccines, Inc. Spray freeze-dried compositions
KR20030025480A (ko) * 2001-09-21 2003-03-29 보령제약 주식회사 약독화 수두 생바이러스 백신용 무단백질 안정화제
US20060228369A1 (en) * 2005-04-11 2006-10-12 Program For Appropriate Technology In Health Stabilization and preservation of temperature-sensitive vaccines
WO2007038926A1 (en) 2005-10-04 2007-04-12 Alk-Abelló A/S Solid vaccine formulation
MX2009004862A (es) 2006-11-07 2009-07-17 Sanofi Pasteur Biologics Co Estabilizacion de vacunas por liofilizacion.
TW201043267A (en) * 2009-03-19 2010-12-16 Intervet Int Bv In situ constituting a vaccine for administration to a predetermined herd of animals
US9101607B2 (en) 2010-03-31 2015-08-11 Stabilitech Ltd. Method for preserving alum adjuvants and alum-adjuvanted vaccines
KR101884953B1 (ko) 2010-03-31 2018-08-02 스타빌리테크 리미티드 바이러스 입자, 폴리펩타이드 또는 생물학적 물질의 안정화를 위한 부형제
WO2011121306A1 (en) 2010-03-31 2011-10-06 Stabilitech Ltd. Stabilisation of viral particles
KR102049988B1 (ko) 2011-06-24 2019-11-28 머크 샤프 앤드 돔 코포레이션 알루미늄 아주반트를 포함하는 hpv 백신 제제 및 그의 제조 방법
JP6176849B2 (ja) * 2011-07-19 2017-08-09 中外製薬株式会社 アルギニンアミドまたはその類似化合物を含む安定なタンパク質含有製剤
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
JP5931449B2 (ja) * 2012-01-11 2016-06-08 日東電工株式会社 医薬組成物及びその製造方法
GB201406569D0 (en) 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
WO2017179614A1 (ja) * 2016-04-15 2017-10-19 富士フイルム株式会社 マイクロニードルアレイ
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2879202A (en) * 1954-11-05 1959-03-24 American Cyanamid Co Stabilization of live viral vaccines by hexahydric alcohols
DE1617457A1 (de) * 1966-12-16 1972-04-20 Erba Carlo Spa Verfahren zur Stabilisierung von Zubereitungen interferierender Virusprodukte
DE1617350C3 (de) * 1967-06-22 1979-09-06 Behringwerke Ag, 3550 Marburg Verfahren zur Inaktivierung von biologischem Material
US3636191A (en) * 1969-10-08 1972-01-18 Cancer Res Inst Vaccine against viral hepatitis and process
JPS5523253B2 (en]) * 1973-12-28 1980-06-21

Also Published As

Publication number Publication date
AU572162B2 (en) 1988-05-05
EP0130619A3 (en) 1985-04-10
EP0130619B1 (en) 1989-03-15
CA1237076A (en) 1988-05-24
ATE41309T1 (de) 1989-04-15
DE3477139D1 (en) 1989-04-20
KR850002277A (ko) 1985-05-10
KR910005888B1 (ko) 1991-08-06
EP0130619A2 (en) 1985-01-09
JPS6013718A (ja) 1985-01-24
AU2999384A (en) 1985-01-10

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